Sonny Bradley has had a minor operation, which will rule him out for Saturday’s Championship clash at home to play-off rivals West Bromwich Albion.
Luke Berry and Jordan Clark are both closer, but it could be weeks before Town’s skipper could be available.
Manager Nathan Jones said: “Sonny’s had a minor groin op, a hernia op, so he’s a certain amount of days or maybe even weeks away. The others, we monitor every day and are closer.
“We haven’t got massive injuries, it’s just Luke Berry and Clark that are getting closer every day.”
The Hatters will have had a week to prepare to face the Baggies after Saturday’s 3-0 defeat to Birmingham City.
Jones added: “We pick up little knocks now and again, stiffness and tightness with the number of games. People coming in that haven’t played for example. But it’s good competition so we’re happy.”